Intravenous immunoglobulin for overwhelming postsplenectomy infection
نویسندگان
چکیده
منابع مشابه
Overwhelming postsplenectomy infection.
This report aims to deepen the understanding of the pathogenesis, diagnosis, clinical characteristics, and treatment of overwhelming postsplenectomy infection (OPSI). A patient treated at Taihe Hospital for tuberculous OPSI is described, and relevant literature is reviewed. Broad-spectrum antibiotics, suppression of the systemic inflammatory reaction, and anti-shock measures were the keys to th...
متن کاملOverwhelming Postsplenectomy Infection for Splenectomized HCV Patients
Pegylated-interferon (IFN) plus ribavirin remains the most effective therapeutic regimen for patients with chronic hepatitis C interferon. Thrombocytopenia is a common side effect of this treatment, often leading to discontinuation of a potentially curative therapy. Splenectomy was a clinically effective treatment for hepatitis C virus-associated thrombocytopenia. Splenectomy in patients with h...
متن کاملManagement of Overwhelming Postsplenectomy Infection Syndrome
Overwhelming postsplenectomy infection (OPSI) is a rare medical emergency, mainly caused by encapsulated bacteria, shortly progressing from a mild flulike syndrome to a fulminant, potentially fatal, sepsis. The risk of OPSI is higher in children and in patients with underlying benign or malignant hematological disorders. The identification of Howell-Jolly bodies on peripheral blood examination ...
متن کاملPurpura Fulminans Associated with Overwhelming Postsplenectomy Infection
A 37-year-old Japanese woman was referred to our institute with a 1-day history of a fever and altered mental status. Physical examinations revealed non-palpable purpura on her face, trunk, and extremities (Picture 1, 2). Blood tests revealed marked thrombocytopenia and hypofibrinogenemia. A detailed chart review showed that she had undergone splenectomy 10 years prior and had not been vaccinat...
متن کاملOverwhelming Postsplenectomy Infection: A Prospective Multicenter Cohort Study.
BACKGROUND Recent population-based cohort studies have questioned the role of pneumococci as the most frequent pathogen causing severe infection in patients after splenectomy. The aim of the study was to define the causative pathogens and clinical presentation of patients with overwhelming postsplenectomy infection (OPSI). METHODS In a prospective cohort study in 173 German intensive care uni...
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ژورنال
عنوان ژورنال: Journal of Global Infectious Diseases
سال: 2021
ISSN: 0974-777X
DOI: 10.4103/jgid.jgid_93_19